Randomized, double-blind, crossover study comparing DFN-11 injection (3 mg subcutaneous sumatriptan) with 6 mg subcutaneous sumatriptan for the treatment of rapidly-escalating attacks of episodic migraine
نویسندگان
چکیده
منابع مشابه
Comparison between Intravenous Sodium Valproate and Subcutaneous Sumatriptan for Treatment of Acute Migraine Attacks; Double-Blind Randomized Clinical Trial
Background: Sodium valproate (SV) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. We compared the efficacy and safety of intravenous SV and subcutaneous Sumatriptan in managing acute migraine attacks. Methods: This double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous SV a...
متن کاملTreatment of acute migraine with subcutaneous sumatriptan.
Sumatriptan succinate, a 5-HT1D receptor agonist, constricts human cranial arteries. Two parallel-group trials for treatment of acute migraines were conducted in the United States. Adult patients were randomized and given either 6 mg of sumatriptan succinate subcutaneously (n = 734) or placebo (n = 370). At 1 hour, sumatriptan was significantly more effective than placebo in reducing moderate o...
متن کاملcomparison between intravenous sodium valproate and subcutaneous sumatriptan for treatment of acute migraine attacks; double-blind randomized clinical trial
background: sodium valproate (sv) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. we compared the efficacy and safety of intravenous sv and subcutaneous sumatriptan in managing acute migraine attacks. methods: this double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous sv a...
متن کاملComparison between Intravenous Sodium Valproate and Subcutaneous Sumatriptan for Treatment of Acute Migraine Attacks; Double-Blind Randomized Clinical Trial
BACKGROUND Sodium valproate (SV) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. We compared the efficacy and safety of intravenous SV and subcutaneous Sumatriptan in managing acute migraine attacks. METHODS This double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous SV a...
متن کاملHuman factors validation study of 3 mg sumatriptan autoinjector, for migraine patients
BACKGROUND Migraine pain relief is reported by more than 50% of patients who receive low dose (3 mg) of sumatriptan. Currently, there is no two-step autoinjector of low-dose sumatriptan available on the market for acute migraine treatment. To fulfill this need, a fully assembled, single-dose, subcutaneous autoinjector (sumatriptan 3 mg; product-code DFN-11) was developed. The device allows for ...
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ژورنال
عنوان ژورنال: The Journal of Headache and Pain
سال: 2017
ISSN: 1129-2369,1129-2377
DOI: 10.1186/s10194-016-0717-7